XTT (2,3-Bis-(2-methoxy-4-nitro-5-sulfophenyl) -2H-tetrazolium-5-carboxanilide)
xtt sodium
CAS: 111072-31-2
Molecular Formula: C22H18N7NaO13S2
XTT (2,3-Bis-(2-methoxy-4-nitro-5-sulfophenyl) -2H-tetrazolium-5-carboxanilide) - Names and Identifiers
| Name | xtt sodium |
| Synonyms | XTT xttsodium xtt sodium XTT sodium salt XTT SODIUM CELL CULTURE TESTED XTT (2,3-Bis-(2-methoxy-4-nitro-5-sulfophenyl) -2H-tetrazolium-5-carboxanilide) 2,3-Bis(2-methoxy-4-nitro-5-sulphophenyl)-2H-tetrazolium-5-carboxanilide inner salt SODIUM 3,3'-[1-[(PHENYLAMINO)CARBONYL]-3,4-TETRAZOLIUM]BIS (4-METHOXY-6-NITRO)BENZENE SULFONIC ACID HYDRATE SODIUM-3,3-[1-[(PHENYLAMINO)CARBONYL]-3,4-TETRAZOLIUM]-BIS(4-METHOXY-6-NITRO)BENZENE SULPHONIC ACID HYDRATE |
| CAS | 111072-31-2 |
| EINECS | 601-039-1 |
| InChI | InChI=1/C22H19N7O13S2.2Na.H2O/c1-41-18-8-16(28(31)32)20(43(35,36)37)10-14(18)26-12-25(22(30)23-13-6-4-3-5-7-13)24-27(26)15-11-21(44(38,39)40)17(29(33)34)9-19(15)42-2;;;/h3-12H,1-2H3,(H,23,30)(H,35,36,37)(H,38,39,40);;;1H2/q+2;2*+1;/p-2 |
XTT (2,3-Bis-(2-methoxy-4-nitro-5-sulfophenyl) -2H-tetrazolium-5-carboxanilide) - Physico-chemical Properties
| Molecular Formula | C22H18N7NaO13S2 |
| Molar Mass | 675.53 |
| Melting Point | 285 ℃ (decompose) |
| Water Solubility | Soluble in hot water at 2.5mg/ml.Soluble in water, dimethyl sulfoxide, dimethyl formamide and phosphate buffered saline.at pH =7.2. |
| Solubility | hot water: 2.5mg/mL |
| Appearance | Yellow powder |
| Color | Yellow |
| Maximum wavelength(λmax) | ['286 nm'] |
| Storage Condition | 2-8°C |
| MDL | MFCD00083517 |
XTT (2,3-Bis-(2-methoxy-4-nitro-5-sulfophenyl) -2H-tetrazolium-5-carboxanilide) - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| HS Code | 29339900 |
XTT (2,3-Bis-(2-methoxy-4-nitro-5-sulfophenyl) -2H-tetrazolium-5-carboxanilide) - Reference
| Reference Show more | 1. Su Yanfeng, Chen Xinhui, Li Meng et al. Optimization of fermentation conditions of Lactobacillus paracasei and evaluation of fermentation broth efficacy [J]. Daily chemical industry 2020 v.50;No.334(06):49-54 73. 2. Sun Yingying, Sun Liping. Experimental Study on Regulation of Spleen Lymphocyte Proliferation in Lung Qi Deficiency Mice by Yiqi Guben Capsule [J]. Chinese Integrated Traditional Chinese and Western Medicine Pediatrics, 2013, 5(001):5-8. 3. Li Shanshan, Sun Liping. Effect of Yiqi Guben Capsule on Regulation of Spleen Lymphocyte Proliferation and Related Organ Index in Spleen-Qi Deficiency Asthma Model Mice [J]. Chinese Integrated Traditional Chinese and Western Medicine Pediatrics, 2013,5(01):17-20. 4. Zhang Jinduo, Su Gang, Lu Yawen, et al. In vitro Study on Curcumol Inducing Cholangiocarcinoma Cell Apoptosis and Regulating Cell Cycle [J]. Journal of Lanzhou University (Medical Edition), 2018, 044(001):65-70. 5. [IF = 9.028] Tao Luo et al."Metal-Free Electro-Activated Sulfite Process for As(III) Oxidation in Water Using Graphite Electrodes." Environ Sci Technol. 2020;54(16):10261-10269 6. [IF = 7.086] Tao Luo et al."Strengthening arsenite oxidation in water using metal-free ultrasonic activation of sulfite." Chemosphere. 2021 Oct;281:130860 7. [IF = 6.498] Zhen Zhu et al."Combination of microwave discharge electrodeless lamp and a TiO2/HZSM-5 composite for the photocatalytic degradation of dimethyl sulphide." Environ Res. 2021 Jun;197:111082 8. [IF = 3.963] Yu Zhang et al."Antifungal effect of volatile organic compounds produced by Pseudomonas chlororaphis subsp. aureofaciens SPS-41 on oxidative stress and mitochondrial dysfunction of Ceratocystis fimbriata." Pestic Biochem Phys. 2021 Mar;173:104777 9. [IF = 3.361] Qiang Li et al."Phosphonium-based ionic liquids as antifungal agents for conservation of heritage sandstone." Rsc Adv.2022 Jan;12(4):1922-1931 10. [IF = 11.236] Yi Yang et al."Self-defense mechanisms of microorganisms from the antimicrobial effect of silver nanoparticles: highlight the role of extracellular polymeric substances." Water Res. 2022 Apr;:118452 |
XTT (2,3-Bis-(2-methoxy-4-nitro-5-sulfophenyl) -2H-tetrazolium-5-carboxanilide) - Reference Information
| biological applications | Cell proliferation assays; cytotoxicity assays; ecotoxicity assays; neurotoxicity assays; antimicrobial susceptibility testing assays; antifungal susceptibility testing assays; cardiac valve viability assays; Cell viability assay |
| Use | Biochemical research Used for AIDS and cancer testing. XTT has been used in conjunction with phenazine methosulfate (PMS) to screen human cancer cell lines. 1 The tetrazolium dye has also been used to study fungal cell damage, in testing antimicrobial susceptibility of staphylococci, and in Candida |
Last Update：2024-04-09 20:48:19
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XTT (2,3-Bis-(2-methoxy-4-nitro-5-sulfophenyl) -2H-tetrazolium-5-carboxanilide)
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